Leucovorin Calcium 1492-18-8 For Counteracts The Toxic Effects Of These Medications

Product Details:
Place of Origin: China
Brand Name: Filter
Certification: GMP
Model Number: 1492-18-8
Payment & Shipping Terms:
Minimum Order Quantity: Negotiable
Price: Negotiable
Packaging Details: Foil Bag
Delivery Time: within 5hours
Payment Terms: T/T, Western Union, MoneyGram, Bitcoin
Supply Ability: 100kg/Month

Detail Information

Name: Leucovorin Calcium Foam: White Powder
Packing: Foil Bag Min Order Quantity: 50g
Color: White Usage: Injectable
Function: Counteracts The Toxic Effects Of These Medications CAS: 1492-18-8
Purity: 98%min Grade: UPS
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Product Description

Leucovorin Calcium 1492-18-8 For Counteracts The Toxic Effects Of These Medications

Details:

An active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist-type chemotherapeutic drugs.

Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist.

This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity. Check for active clinical trials using this agent.

 

Uses

This medication is used to treat or prevent serious blood cell disorders (such as thrombocytopenia, neutropenia, anemia) caused by certain drugs (folic acid antagonists such as methotrexate, trimethoprim, pyrimethamine).

 

How to use Leucovorin Calcium

Take this medication by mouth with or without food, usually every 6 hours or once daily or as directed by your doctor.

Dosage is based on your medical condition and response to treatment. Doses above 25 milligrams are not recommended.

Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.

Tell your doctor if you are unable to take this medication because of nausea/vomiting. You may need to be switched to the injection form of this medication

 

What Conditions does Leucovorin Calcium Treat?

trimethoprim poisoning

pyrimethamine poisoning

serious side effects from trimetrexate

serious side effects from sulfadiazine

high blood levels of methotrexate

decreased bone marrow function by folic acid antagonism

 

Side Effects

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.

 

Precautions

Before taking leucovorin, tell your doctor or pharmacist if you are allergic to it; or to levoleucovorin; or to folic acid or folinic acid; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using this medication, tell your doctor or pharmacist your medical history, especially of: certain anemias (due to vitamin B12 deficiency).

Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding

 

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