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|Place of Origin:||China|
Payment & Shipping Terms:
|Minimum Order Quantity:||Negotiable|
|Packaging Details:||Foil Bag|
|Delivery Time:||within 5hours|
|Payment Terms:||T/T, Western Union, MoneyGram, Bitcoin|
|Name:||Leucovorin Calcium||Foam:||White Powder|
|Packing:||Foil Bag||Min Order Quantity:||50g|
|Function:||Counteracts The Toxic Effects Of These Medications||CAS:||1492-18-8|
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Leucovorin Calcium 1492-18-8 For Counteracts The Toxic Effects Of These Medications
An active metabolite of folic acid (also called folinic acid and citrovorum factor), which does not require metabolism by dihydrofolate reductase, the molecular target of folate antagonist-type chemotherapeutic drugs.
Leucovorin calcium counteracts the toxic effects of these medications, 'rescuing' the patient while permitting the antitumor activity of the folate antagonist.
This agent also potentiates the effects of fluorouracil and its derivatives by stabilizing the binding of the drug's metabolite to its target enzyme, thus prolonging drug activity. Check for active clinical trials using this agent.
This medication is used to treat or prevent serious blood cell disorders (such as thrombocytopenia, neutropenia, anemia) caused by certain drugs (folic acid antagonists such as methotrexate, trimethoprim, pyrimethamine).
How to use Leucovorin Calcium
Take this medication by mouth with or without food, usually every 6 hours or once daily or as directed by your doctor.
Dosage is based on your medical condition and response to treatment. Doses above 25 milligrams are not recommended.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
Tell your doctor if you are unable to take this medication because of nausea/vomiting. You may need to be switched to the injection form of this medication
What Conditions does Leucovorin Calcium Treat?
serious side effects from trimetrexate
serious side effects from sulfadiazine
high blood levels of methotrexate
decreased bone marrow function by folic acid antagonism
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
A very serious allergic reaction to this drug is rare. However, seek immediate medical attention if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Before taking leucovorin, tell your doctor or pharmacist if you are allergic to it; or to levoleucovorin; or to folic acid or folinic acid; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor.It is unknown if this medication passes into breast milk. Consult your doctor before breast-feeding
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