
White Cardarine Weight Loss PPAR Delta Agonist Treat Obesity Performance Enhancing
Product Details:
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Place of Origin: | China |
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Brand Name: | Filter |
Certification: | GMP |
Model Number: | 431579-34-9 |
Payment & Shipping Terms:
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Minimum Order Quantity: | 10G |
Price: | Negotiable |
Packaging Details: | Foil Bag |
Delivery Time: | 3-7days |
Payment Terms: | Western Union, MoneyGram, T/T, |
Supply Ability: | 1000KG |
Detail Information |
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Model NO: | CAS 431579-34-9 | Usage: | Building Muscle, Burning Fat And Gaining Strength |
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Specification: | USP/BP | Shipment: | EMS, FedEx, TNT, DHL, UPS |
Polciy: | Re-Shipping Policy | Payment: | Western Union, Moneygram, T/T |
High Light: | fat burning sarms,selective androgen receptor modulator |
Product Description
Sarm GW-501516 for Bodybuilding
Description:
GW501516 (also known as GW-501,516, GW1516, GSK-516) is a PPAR& receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s, was entered into clinical development as a drug candidate for metabolic diseases and cardiovascular diseases, and was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.
Application:
GW501516 is a selective agonist (activator) of the PPARδ receptor. It displays high affinity (Ki = 1 nM) and potency (EC50 = 1 nM) for PPARδ with > 1000 fold selectivity over PPARα and PPARγ.
In rats, binding of GW501516 to PPARδ recruits the co activator PGC-1a. The PPARδ/coactivator complex in turn up regulates the expression of proteins involved in energy expenditure. Furthermore in rats treated with GW501516, increased fatty acid metabolism in skeletal muscle and protection against diet-induced obesity and type II diabetes was observed.
In obese rhesus monkeys, GW501516 increased high-density lipoprotein (HDL) and lowered very-low-density lipoprotein (VLDL). The mechanism by which PPARδ agonists increase HDL appears to be a result of increased expression of the cholesterol transporter ABCA1
Dosage:
The regular dosage of Cardarine is 10 to 20 mg per day. 10 mg a day is aimed for endurance, and the higher the dosage the greater the fat loss benefits are going to be.
Expect to experience more intense endurance and fat burning when taking 20 mgs, but you never want to take much more than that.
You can take it once a day or split the dosage (in the AM and PM). GW 501516 is best taken 30-45 minutes before a workout. You'll feel the difference the first time you take it.
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Cardarine is extremely effective at low dosages of 10 to 20mg per day. If you don’t have any experience with GW501516, most users will advise to start out with a low dosage.
Even at 10mg per day, you will be able to experience a significant increase in performance. Due to the fact that this compund is very potent, it’s not recommended to go any higher than 20mg per day.
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