Raw Powder Aicar Sarm Powder AICAR 50mg Per Vial Crystalline Solid Formulation

Product Details:
Place of Origin: Shanghai
Brand Name: Filter
Certification: GMP
Model Number: 841205-47-8
Payment & Shipping Terms:
Minimum Order Quantity: 10bottles
Price: Negotiable
Packaging Details: Foil Bag
Delivery Time: 1~3days
Payment Terms: Western Union, MoneyGram, T/T,Bitcoin
Supply Ability: 100kg per month

Detail Information

Packing: Bottle Purity: 99%min
Appearance: Liquid Color: White
Function: Bodybuilding Usage: Injection
Chemical: AICAR
High Light:

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injectable anabolic steroids

Product Description

99%min Purity Sarms Raw Powder AICAR for Building Muscle 50mg/vial

AICAR (AICA-Riboside) strongly inhibits the transcription of PPAR&alpha and the coactivation of PPAR&alpha. In adipocyte studies it has been shown to antagonize lipolysis induced by isoprenaline and has been suggested for use in kinase cascade research. Additionally, research indicates that AICAR blocks the differentiation of 3T3-L1 (sc-2243) adipocytes. Studies demonstrate that AICAR can mimic the activity of insulin (sc-211647) by activating AMPK (AMP-activated protein kinase), and affecting the expression of PEPCK-M (PEPCK) and glucose-6-phosphatase (G6Pase). The 5-aminoimidazole-4-carboxamide ribonucleoside (ZMP) is the monophosphorylated derivative of AICA-Riboside, and it can serve as the substrate for the aminoimidazole carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase (ATIC). AICAR is an inhibitor of Hsp90, mTOR and p70 S6 Kinase.

 

Description

AICAR is a cell-permeable adenosine analog that is a selective activator of AMP-activated protein kinase (AMPK) in adipocytes and hepatocytes. The AMPK is a metabolic regulator that inhibits anabolic processes and is active when energy availability is reduced. AICAR is reported to promote osteogenic differentiation of mesenchymal stem cells in vitro and astroglial differentiation in neural stem cells.

 

Additional Information

Applications:

FA

Synonyms:

Acadesine, AICA ribonucleoside, aminoimidazole carboxamide ribonucleoside, ARA100,1-ribosyl-4-carboxamido-5-aminoimidazole

Formulation:

Crystalline solid

Chemical Name:

5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide

Molecular Formula:

C9H14N4O5

Molecular Weight:

<div "class="productview-attribute-conten_div">258.2

 

CAS Number

2627-69-2

Purity:

≥98%

Storage Conditions:

Product should be kept at -20°C.

 

References:

Sullivan, J. E., Brocklehurst, K. J., Marley, A. E., Carey, F., Carling, D., & Beri, R. K. (1994). Inhibition of lipolysis and lipogenesis in isolated rat adipocytes with AICAR, a cell-permeable activator of AMP-activated protein kinase. FEBS letters, 353(1), 33-36.

Young, M. E., Radda, G. K., & Leighton, B.

 

(1996). Activation of glycogen phosphorylase and glycogenolysis in rat skeletal muscle by AICAR—an activator of AMP-activated protein kinase. FEBS letters, 382(1), 43-47.

Iglesias, M. A., Ye, J. M., Frangioudakis, G., Saha, A. K., Tomas, E., Ruderman, N. B., ... & Kraegen, E. W. (2002). AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats. Diabetes, 51(10), 2886-2894.

 

 

 

Raw Powder Aicar Sarm Powder AICAR 50mg Per Vial Crystalline Solid Formulation 0

Raw Powder Aicar Sarm Powder AICAR 50mg Per Vial Crystalline Solid Formulation 1

 


 

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